Chronic Fatigue Syndrome (CFS) is a debilitating medical condition that is characterized by extreme fatigue and tiredness that cannot be attributed to another diagnosable medical condition, is not improved by rest and may be worsened after physical activity or prolonged mental activity. In Europe and Canada, patients with symptoms similar to CFS are diagnosed with a condition known as Myalgic Encephalomyelitis (ME).

Because laboratory tests to diagnose CFS/ME are not currently available, a CFS diagnosis is made if an individual has the presence of the following 3 criteria:

1. The individual has had severe chronic fatigue for 6 or more consecutive months that is not due to prolonged exertion or other medical conditions associated with fatigue.

2. The fatigue significantly interferes with usual daily activities or work.

3. The individual has 4 or more of the following symptoms which have persisted for at least 6 months:

  1.     • Tiredness following exercise or exertion that lasts for more than 24 hours
  2.     • Unrefreshing sleep
  3.     • Impaired short-term memory or concentration
  4.     • Muscle pain
  5.     • Pain in the joints without swelling or redness
  6.     • Headaches of a new type, pattern, or severity
  7.     • Recurring sore throats
  8.     • Tender glands in the neck or armpit

The cause of CFS/ME is not yet known and the condition may come on suddenly or gradually. At this time there are no FDA approved treatments leaving medical care to focus solely on the treatment of symptoms.

The Synergy Trial seeks to investigate a treatment that is potentially safe and effective at alleviating some or all of the symptoms associated with CFS/ME.

For more information on the Synergy Trial call 1-855-318-HOPE (4673).